Product Name:

Metformin (Brand Name: Glucophage) Subscription

Short Description

Metformin is the most widely prescribed, FDA-approved oral medication for type 2 diabetes. As an adjunct to diet and exercise, it helps lower blood glucose levels by reducing liver glucose production, decreasing intestinal glucose absorption, and increasing insulin sensitivity.

Beyond blood sugar control, metformin has been studied for its potential to reduce all-cause mortality and support health in conditions such as pre-diabetes, cancer, inflammation, neurodegeneration, cardiovascular disease, liver disease, and other age-related conditions.*

Full Description

Potential Benefits:*

• May enhance healthspan and extend lifespan (source, source) 
• Delay or prevent type 2 diabetes
• Help with weight loss (source)
• Reduce blood glucose levels
• Increase insulin sensitivity (source)
• Improve prognosis for cancer patients and may even help prevent cancer (source, source)
• Help with cardiovascular disease (source, source)
• Decrease inflammation (source)
• Reduce risk of cognitive impairment and dementia (source, source)
• Ease negative effects of stopping testosterone replacement therapy (source)

Common Side Effects:

• Rash

• Dizziness

• Itching/swelling

• Shortness of breath

• Nausea and vomiting

• Upset stomach

• Diarrhea

• Weakness

• Chest discomfort

• Infections

• Weight loss

• Metallic taste in the mouth

Important Notes:

• Vitamin B12 Levels: Metformin may reduce vitamin B12 absorption, which can rarely lead to anemia. A B12 supplement may be recommended.

• Usage & Dosage: Metformin is taken orally with food daily. Your prescribed dosage will be based on your medical condition, treatment response, and other medications. Follow your provider’s guidance for safe use.

Metformin is FDA-approved for type 2 diabetes, but multiple third-party studies suggest additional benefits, leading to its use in “off-label” prescriptions. Prescription products require an online evaluation with a licensed medical professional. While some studies have been conducted on animal models, ongoing clinical trials are assessing its full range of benefits in humans (source).

Frequently Asked Questions

What are common side effects, and what should I do if I experience them?

The most common side effects include nausea, diarrhea, dizziness, stomach upset, and a metallic taste. If you experience any concerning side effects, please contact your healthcare provider.

How does metformin affect vitamin B12 levels?

Metformin may decrease B12 absorption, which can rarely lead to anemia. Taking a B12 supplement may be recommended to counteract this effect.

Metformin gives me a stomach ache. What should I do?

Gastrointestinal issues are common when starting metformin. Reducing the dose initially and gradually increasing it can help your body adjust. Taking it with food may also minimize discomfort.

How does metformin lower blood sugar, and can I take it if I have hypoglycemia?

Metformin helps lower blood sugar by:

1. Reducing liver glucose production

2. Decreasing glucose absorption from food

3. Increasing insulin sensitivity

If you have a history of hypoglycemia, your doctor will assess whether metformin is appropriate and adjust the dosage accordingly.

How do I know if metformin is working?

Monitoring blood sugar levels before and during treatment is the best way to track metformin’s effectiveness. Over time, lower glucose levels and improved energy may indicate better insulin function. Long-term benefits, such as cardiovascular protection and diabetes prevention, may not be immediately noticeable but contribute to overall health.

How long should I take metformin?

Studies suggest that the longer metformin is taken, the greater its long-term benefits. Your doctor will help determine the best duration based on your health needs.

Is metformin safe?

Yes. Metformin is listed on the World Health Organization’s Model List of Essential Medicines, a catalog of the most effective, safe, and cost-efficient treatments available.

Why is follow-up testing required every 90 days?

Regular blood tests help ensure metformin is safe and effective for you. Follow-up labs include:

• ALT & AST levels (to monitor liver function)

• Creatinine levels (to assess kidney function)

Your healthcare provider will review your results and follow up if needed.