Benefits

• Weight loss (7-11% after a year of treatment)
• Improvement in systolic and diastolic blood pressure
• Improvement in A1C levels in diabetic patients
• Helps to keep weight off over time
• May help improve indicators of heart disease, high blood pressure, type 2 diabetes, and stroke
• May improve energy, mobility, joint pain

Side-effects

• Shortness of breath
• Headache
• Dizziness
• Numbness, burning, or tingling in the hands, feet, face, or mouth
• Difficulty falling or staying asleep
• Decreased sense of touch or ability to feel sensation
• Difficulty concentrating, thinking, paying attention, speaking, or remembering
• Excessive tiredness
• Dry mouth
• Unusual thirst
• Changes or decreased ability to taste food
• Nausea
• Diarrhea
• Constipation
• Heartburn
• Painful menstrual periods
• Pain in the back, neck, muscles, arms or legs
• Tightening of the muscles
• Painful, difficult, or frequent urination
• Hair loss
• Fever, sore throat, cough, congestion, or other signs of infection

It should not be taken if you are pregnant, have glaucoma, have hyperthyroidism, or are currently taking or have stopped monoamine oxidase inhibitors within the past 14 days of starting treatment.

Black Box Warning: Phentermine & Topiramate comes with several warnings and precautions that individuals should be aware of: Embryo-Fetal Toxicity, Increase in Heart Rate, Suicidal Behavior and Ideation, Risk of Ophthalmologic Adverse Reactions, Mood and Sleep Disorders, Cognitive Impairment, Slowing of Linear Growth, Metabolic Acidosis, Decrease in Renal Function, Risk of Seizures with Abrupt Withdrawal of Phentermine & Topiramate, Kidney Stones, Oligohydrosis and Hyperthermia, Hypokalemia, Serious Skin Reactions.