Zofran (Ondansetron): Benefits, Side Effects, and Considerations Follow Benefits Convenience and quick onset of action Provides nausea relief during GLP-1 Treatment Provides nausea relief during chemotherapy and radiation therapy Provides post-surgery relief from nausea Helps with morning sickness Helps with migraine headache nausea Helps to reduce inflammation Helps to maintain hydration status Relatively low risk for medication complications Side-effects Headache Drowsiness or sedation Rash, hives, or itching Confusion Dizziness Malaise or fatigue Chills Diarrhea Constipation Blurred vision or vision loss Swelling of the face, lips, mouth, tongue, or throat Sensation of warmth or flushing Excessive sweating Irregular heart rate Low blood pressure Trouble breathing Cough Anxiety or agitation Urinary retention Asymptomatic increase in AST/ALT Loss of coordination Related articles Bi-Est Cream (E3/E2): Benefits, Side Effects, and Considerations